Pathophysiologie der obstruktiven Schlafapnoe

Translated title of the contribution: Pathophysiology of obstructive sleep apnea

C. Heiser, D. Eckert

Research output: Contribution to journalReview articlepeer-review

3 Citations (Scopus)

Abstract

The prevalence of obstructive sleep apnea (OSA) is considered to be very high in western industrialized countries. There are conservative and surgical forms of treatment for OSA; however, the pathophysiology is largely unexplained and cannot be explained by anatomical abnormalities alone. In recent years, a number of non-anatomical factors have been found that favor the development of OSA. These include the respiratory excitation threshold (arousals), the respiratory drive (loop gain), as well as the control and function of the muscular upper airway dilators. The understanding of the individual pathophysiological processes may be helpful in the future to develop individual treatment approaches for patients.

Translated title of the contributionPathophysiology of obstructive sleep apnea
Original languageGerman
Pages (from-to)654-662
Number of pages9
JournalHNO
Volume67
Issue number9
DOIs
Publication statusPublished - 1 Sep 2019

Keywords

  • Arousal
  • Loop gain
  • Respiratory drive
  • Sleep-disordered breathing disorders
  • Upper airway

Fingerprint Dive into the research topics of 'Pathophysiology of obstructive sleep apnea'. Together they form a unique fingerprint.

Cite this