Patiëntenperspectief in de beoordeling van direct werkende orale anticoagulantia bij atriumfibrilleren en veneuze trombo-embolie

Translated title of the contribution: Patients' perspective in the decision and reimbursement process for direct-acting oral anticoagulants for atrial fibrillation and venous thromboembolic disease

J. R.B.J. Brouwers, Jeroen Hendriks, Hans Van Laarhoven, Gerlof J. Jukema, Marja H. Pronk

Research output: Contribution to journalArticle

Abstract

OBJECTIVE: To develop a method to incorporate practice-based knowledge of medical doctors, pharmacists, nurses and patients in treatment guidelines and in reimbursement decisions. DESIGN AND METHODS: Based on literature review and expert opinion of medical professionals a decision tree is developed for assessment of DOACs from patients' perspective in the treatment of non-valvular atrial fibrillation [nvAF] and venous thromboembolic disease (VTE). RESULTS: For both nvAF and VTE six relevant patient aspects were identified: target INR, safe use, therapy compliance, organisation of care, wellbeing and self-management. When comparing DOACs with standard VKA-containing treatment for these conditions, DOACs showed added value regarding four patient aspects in nvAF and five aspects in VTE. As an example, relevant aspects for DOACs are: easy dosage regimen, self-management of drug use and wellbeing. None of these aspects are represented in the current decision process for guidelines and reimbursement. CONCLUSION: Dealing with relevant criteria from a patients' perspective in a decision tree, DOACs have potential added value that should be considered in guideline development and reimbursement decisions.

Translated title of the contributionPatients' perspective in the decision and reimbursement process for direct-acting oral anticoagulants for atrial fibrillation and venous thromboembolic disease
Original languageDutch
Pages (from-to)72-78
Number of pages7
JournalPharmaceutisch Weekblad
Volume150
Issue number16
Publication statusPublished - 2015
Externally publishedYes

Keywords

  • practice-based knowledge
  • Patients' perspective
  • reimbursement process
  • oral anticoagulants
  • atrial fibrillation
  • venous thromboembolic disease

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