Pattern recognition of single-molecule force spectroscopy data

Michael Kuhn, Harald Janovjak, Maurice Hubain, Dirk Labudde, Daniel J. Müller

Research output: Contribution to specialist publicationArticle

1 Citation (Scopus)

Abstract

The detection of molecular forces that stabilize single proteins is possible with ultrasensitive force probe methods such as the atomic force microscope. Forces applied during continuous stretching of the molecule are measured by the deflection of cantilever. It is expected that in future, high-throughput force spectroscopy assays will permit screening of physiologically relevant parameters. A software solution was developed to allow high-throughput classification and statistical analysis of force spectra.

Original languageEnglish
Pages50-51
Number of pages2
Volume12
No.8
Specialist publicationBiophotonics International
Publication statusPublished - Aug 2005
Externally publishedYes

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