Peptide-containing nerves in the urinary bladder of the toad, Bufo marinus

Research output: Contribution to journalArticlepeer-review

16 Citations (Scopus)


The distributions of peptide-containing nerves in the urinary bladder of the toad, Bufo marinus, were studied by means of fluorescence immunohistochemistry of whole-mount preparations. The bundles of smooth muscle in the bladder are well supplied by varicose nerve fibres displaying somatostatin-like immunoreactivity; these fibres probably arise from intrinsic perikarya. The urinary bladder also has a well-developed plexus of nerves containing substance P-like immunoreactive material; these elements probably represent sensory nerves of extrinsic origin. Nerve fibres showing immunoreactivity to vasoactive intestinal polypeptide (VIP) or enkephalin are rare within the urinary bladder of the toad. It is considered unlikely that any of these peptides directly mediates the hyoscine-resistant excitatory response of the smooth muscle to nerve stimulation in the toad bladder.

Original languageEnglish
Pages (from-to)137-144
Number of pages8
JournalCell and Tissue Research
Issue number1
Publication statusPublished - Jan 1983
Externally publishedYes


  • Peptide-containing nerves
  • Toad (Bufo marinus)
  • Urinary bladder


Dive into the research topics of 'Peptide-containing nerves in the urinary bladder of the toad, Bufo marinus'. Together they form a unique fingerprint.

Cite this