Pharmacology of ionotropic glutamate receptors: A structural perspective

Philipp Stawski; Harald Janovjak; Dirk Trauner

doi:10.1016/j.bmc.2010.09.012

Pharmacology of ionotropic glutamate receptors: A structural perspective

Philipp Stawski, Harald Janovjak, Dirk Trauner

Research output: Contribution to journal › Review article › peer-review

55 Citations (Scopus)

Abstract

The impact of structural biology on the design of ligands (agonists, antagonists and modulators) for ionotropic glutamate receptors is reviewed.

Original language	English
Pages (from-to)	7759-7772
Number of pages	14
Journal	Bioorganic & Medicinal Chemistry
Volume	18
Issue number	22
DOIs	https://doi.org/10.1016/j.bmc.2010.09.012
Publication status	Published - 15 Nov 2010
Externally published	Yes

Keywords

Agonist
AMPA receptors
Antagonist
Clamshell
Ionotropic glutamate receptors
Kainate receptors
Neurotransmitter
NMDA receptors
Receptor desensitization

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title = "Pharmacology of ionotropic glutamate receptors: A structural perspective",

abstract = "The impact of structural biology on the design of ligands (agonists, antagonists and modulators) for ionotropic glutamate receptors is reviewed.",

keywords = "Agonist, AMPA receptors, Antagonist, Clamshell, Ionotropic glutamate receptors, Kainate receptors, Neurotransmitter, NMDA receptors, Receptor desensitization",

author = "Philipp Stawski and Harald Janovjak and Dirk Trauner",

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AU - Janovjak, Harald

AU - Trauner, Dirk

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KW - Antagonist

KW - Clamshell

KW - Ionotropic glutamate receptors

KW - Kainate receptors

KW - Neurotransmitter

KW - NMDA receptors

KW - Receptor desensitization

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JO - Bioorganic & Medicinal Chemistry

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Pharmacology of ionotropic glutamate receptors: A structural perspective

Abstract

Keywords

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