Physiology of Gastric Motility Patterns

Grant W. Henning, Nicholas Spencer

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

5 Citations (Scopus)


This chapter discusses major recent advances that have been made in our understanding of intrinsic myogenic control mechanisms of the stomach and the complex interactions between intrinsic excitatory and inhibitory nerve endings, interstitial cells of Cajal, and smooth muscle cells. Advances will also be discussed in our understanding of the functional implications of the importance of Ca2+-activated chloride channels in pacemaker activity in the gastric musculature. Finally, major recent advances will be revealed in our understanding of the spinal afferent innervation of the stomach and esophagus, which underlie the detection of noxious and innocuous stimuli from the upper gastrointestinal tract.

Original languageEnglish
Title of host publicationPhysiology of the Gastrointestinal Tract
Subtitle of host publicationSixth Edition
EditorsHamid M Said
PublisherElsevier/Academic Press
Number of pages16
ISBN (Electronic)9780128124260
ISBN (Print)9780128099544
Publication statusPublished - 28 Mar 2018


  • Gastric Motility Patterns
  • stomach
  • upper gastrointestinal tract
  • Gastric antrum
  • Spinal afferent
  • Pacemaker cell
  • Pain
  • Interstitial cell of Cajal
  • Peristalsis


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