PLASMA NEUROPEPTIDE Y AND ATRIAL NATRIURETIC PEPTIDE CONCENTRATIONS IN MAN

A. E. Russell, P. E. Aylward, S. A. Smith, M. D. Cain, R. J. McRitchie, J. P. Chalmers

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

1. In order to examine the concentration of neuropeptide Y‐like immuno‐reactivity (NPY‐LI) and atrial natriuretic peptide (ANP) in the circulation in man, blood was sampled from the iliac vein, the inferior vena cava, the superior vena cava, the pulmonary artery and the femoral artery in 13 patients undergoing cardiac catheterization. 2. Plasma NPY‐LI levels were similar at all points sampled and no arteriovenous differences were found. Plasma ANP concentration in the pulmonary artery was greater than in peripheral venous blood but there was a strong correlation between the two. 3. The concentration of NPY‐LI and ANP in peripheral venous blood reflects central venous and arterial concentrations.

Original languageEnglish
Pages (from-to)955-958
Number of pages4
JournalClinical and Experimental Pharmacology and Physiology
Volume15
Issue number12
DOIs
Publication statusPublished - Dec 1988

Keywords

  • atrial natriuretic peptide
  • human
  • neuropeptide Y.

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