Abstract
Post-hepatectomy liver failure (PHLF) is a serious and often life-threatening complication which manifests with progressive jaundice, coagulopathy, frequent renal failure, ascites and encephalopathy. Historically, PHLF has been a poorly defined entity but there have been recent attempts to produce a definition incorporating the timing, degree of jaundice and coagulopathy. In this chapter, we will discuss the clinical issues and provide the reader with a comprehensive understanding of PHLF, and its management (including mitigating preoperative, operative and postoperative risk factors) based on the current evidence in the literature.
| Original language | English |
|---|---|
| Title of host publication | Bailey & Love’s Essential Operations in Hepatobiliary and Pancreatic Surgery |
| Editors | Ashley R. Dennison, Guy J. Maddern, Jia Fan |
| Publisher | CRC Press/Balkema |
| Chapter | 20 |
| Pages | 145-150 |
| Number of pages | 6 |
| ISBN (Electronic) | 9781040027196 |
| ISBN (Print) | 9780367530006 |
| DOIs | |
| Publication status | Published - 2024 |