Post-operative cognitive dysfunction after total joint replacement in the elderly: A meta-analysis: A meta-analysis

Julia Scott, Jane Mathias, Anthony Kneebone

    Research output: Contribution to journalReview article

    25 Citations (Scopus)

    Abstract

    This meta-analysis consolidated the research on postoperative cognitive dysfunction (POCD) following total joint arthroplasty (TJA). Data from 17 studies that assessed cognition pre- and post-surgery in TJA patients alone (15 studies) or matched TJA and control groups (2 studies) were analysed. Results were grouped by cognitive domain (memory, attention, language, speed, general cognition) and follow-up interval (pre-discharge, 3-6. months post-surgery). The TJA data revealed small declines in reaction time and general cognition pre-discharge, but no evidence of decline 3-6. months post-surgery. Very limited TJA and Control data indicated no group differences in the changes to performance over time; however, the TJA group was cognitively compromised pre- and post-surgery compared to Controls. Further appropriately controlled research is required to clarify whether POCD commonly occurs after TJA.

    Original languageEnglish
    Pages (from-to)261-267
    Number of pages7
    JournalJournal of Arthroplasty
    Volume29
    Issue number2
    DOIs
    Publication statusPublished - 2014

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