Postinfectious brainstem encephalitis associated with SARS-CoV-2

Anthony Khoo, Benjamin McLoughlin, Sanjay Cheema, Rimona S. Weil, Christian Lambert, Hadi Manji, Michael S. Zandi, Jasper M. Morrow

Research output: Contribution to journalLetterpeer-review

67 Citations (Scopus)


Immune-mediated neurological sequelae following infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are becoming increasingly evident, and can affect both the peripheral and central nervous system. We report a postinfectious brainstem syndrome in a patient with COVID-19 who presented with generalised myoclonus, ocular flutter with convergence spasm and acquired hyperekplexia. Clinical improvement was seen following corticosteroids, highlighting this as a possible treatment in patients where a post-COVID-19 autoimmune encephalitis is suspected.
Original languageEnglish
Pages (from-to)1013-1014
Number of pages2
JournalJournal of Neurology, Neurosurgery and Psychiatry
Issue number9
Early online date7 Jul 2020
Publication statusPublished - 1 Sept 2020
Externally publishedYes


  • encephalitis
  • COVID-19
  • SARS-CoV-2
  • Case report


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