TY - JOUR
T1 - Potential role of cannabidiol for seizure control in a patient with recurrent glioma
AU - Hsu, Kristin
AU - Whitham, Emma
AU - Kichenadasse, Ganessan
PY - 2020/1
Y1 - 2020/1
N2 - Glioma-related epilepsy significantly impact on patients’ quality of life, and can often be difficult to treat. Seizures cause significant morbidity for example neurocognitive deterioration, which may result from seizures themselves or due to adverse effects from antiepileptic drugs. Management of tumour with surgery, radiotherapy and chemotherapy may contribute to seizure control, but tumour related epilepsy is often refractory despite adequate treatment with standard anti-epileptic medications. Given the increasing interest in medicinal cannabis (or cannabidiol or CBD) as an anti-epileptic drug, CBD may help with seizure control in glioma patients with treatment-refractory seizures. Here we present a case of a young lady with recurrent glioma who had refractory seizures despite multiple anti-epileptic agents, who had significant benefit with CBD.
AB - Glioma-related epilepsy significantly impact on patients’ quality of life, and can often be difficult to treat. Seizures cause significant morbidity for example neurocognitive deterioration, which may result from seizures themselves or due to adverse effects from antiepileptic drugs. Management of tumour with surgery, radiotherapy and chemotherapy may contribute to seizure control, but tumour related epilepsy is often refractory despite adequate treatment with standard anti-epileptic medications. Given the increasing interest in medicinal cannabis (or cannabidiol or CBD) as an anti-epileptic drug, CBD may help with seizure control in glioma patients with treatment-refractory seizures. Here we present a case of a young lady with recurrent glioma who had refractory seizures despite multiple anti-epileptic agents, who had significant benefit with CBD.
KW - Anti-epileptic
KW - Cannabidiol
KW - Epilepsy
KW - Glioma
KW - Treatment-refractory
UR - http://www.scopus.com/inward/record.url?scp=85076555066&partnerID=8YFLogxK
U2 - 10.1016/j.jocn.2019.11.024
DO - 10.1016/j.jocn.2019.11.024
M3 - Article
AN - SCOPUS:85076555066
VL - 71
SP - 275
EP - 276
JO - Journal of Clinical Neuroscience
JF - Journal of Clinical Neuroscience
SN - 0967-5868
ER -