Predictors of 1-Year Survival after Endovascular Aneurysm Repair

Robert A. Fitridge; Margaret Boult; Tania De Loryn; Prudence A. Cowled; Mary B. Barnes

doi:10.1016/j.ejvs.2015.12.019

Predictors of 1-Year Survival after Endovascular Aneurysm Repair

Robert A. Fitridge, Margaret Boult, Tania De Loryn, Prudence A. Cowled, Mary B. Barnes

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

Abstract

Objective/background The purpose of this study was to determine the preoperative variables that best predict 1-year survival following elective endovascular aneurysm repair (EVAR), a period of time that would suggest the patient had benefited from the procedure. Most EVAR survival studies focus on early and late survival; scant information is available for 1-year survival.

Methods Data from two Australian audits of EVAR (1999-2001 and 2009-13) were combined (n = 1,647). Preoperative variables included routine demographic data, clinical health assessments, computed tomography-derived anatomical data, and all-cause mortality. Univariate and multivariate logistic regressions determined which variables best predicted 1-year survival.

Results One-year survival after EVAR was 93.7% (1,544/1,647) and 30-day survival was 98.4% (1,620/1,647). Univariate analyses found that nine preoperative variables were significantly associated with 1-year survival. Five variables were included in the final multivariate model: American Society of Anesthesiologists physical status, aneurysm diameter, creatinine, respiratory assessment, and severity of iliac artery calcification (receiver-operator curve 0.717, R² =.117). Predicted 1-year survival ranged from 98.6% to 68.0%, based on differences in aneurysm size and patient comorbidities.

Conclusion Personalised 1-year survival risk enables surgeons and patients to consider seriously the risks and benefits of EVAR prior to surgery.

Original language	English
Pages (from-to)	528-534
Number of pages	7
Journal	European Journal of Vascular and Endovascular Surgery
Volume	51
Issue number	4
DOIs	https://doi.org/10.1016/j.ejvs.2015.12.019
Publication status	Published - Apr 2016
Externally published	Yes

Keywords

Abdominal aortic aneurysm
Mortality
Endovascular procedures

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@article{db252fb6f5ea47a38b4f917fed3c8f05,

title = "Predictors of 1-Year Survival after Endovascular Aneurysm Repair",

abstract = "Objective/background The purpose of this study was to determine the preoperative variables that best predict 1-year survival following elective endovascular aneurysm repair (EVAR), a period of time that would suggest the patient had benefited from the procedure. Most EVAR survival studies focus on early and late survival; scant information is available for 1-year survival. Methods Data from two Australian audits of EVAR (1999-2001 and 2009-13) were combined (n = 1,647). Preoperative variables included routine demographic data, clinical health assessments, computed tomography-derived anatomical data, and all-cause mortality. Univariate and multivariate logistic regressions determined which variables best predicted 1-year survival. Results One-year survival after EVAR was 93.7% (1,544/1,647) and 30-day survival was 98.4% (1,620/1,647). Univariate analyses found that nine preoperative variables were significantly associated with 1-year survival. Five variables were included in the final multivariate model: American Society of Anesthesiologists physical status, aneurysm diameter, creatinine, respiratory assessment, and severity of iliac artery calcification (receiver-operator curve 0.717, R2 =.117). Predicted 1-year survival ranged from 98.6% to 68.0%, based on differences in aneurysm size and patient comorbidities. Conclusion Personalised 1-year survival risk enables surgeons and patients to consider seriously the risks and benefits of EVAR prior to surgery.",

keywords = "Abdominal aortic aneurysm, Mortality, Endovascular procedures",

author = "Fitridge, {Robert A.} and Margaret Boult and {De Loryn}, Tania and Cowled, {Prudence A.} and Barnes, {Mary B.}",

year = "2016",

month = apr,

doi = "10.1016/j.ejvs.2015.12.019",

language = "English",

volume = "51",

pages = "528--534",

journal = "European Journal of Vascular and Endovascular Surgery",

issn = "1078-5884",

publisher = "W.B. Saunders Ltd",

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}

TY - JOUR

T1 - Predictors of 1-Year Survival after Endovascular Aneurysm Repair

AU - Fitridge, Robert A.

AU - Boult, Margaret

AU - De Loryn, Tania

AU - Cowled, Prudence A.

AU - Barnes, Mary B.

PY - 2016/4

Y1 - 2016/4

N2 - Objective/background The purpose of this study was to determine the preoperative variables that best predict 1-year survival following elective endovascular aneurysm repair (EVAR), a period of time that would suggest the patient had benefited from the procedure. Most EVAR survival studies focus on early and late survival; scant information is available for 1-year survival. Methods Data from two Australian audits of EVAR (1999-2001 and 2009-13) were combined (n = 1,647). Preoperative variables included routine demographic data, clinical health assessments, computed tomography-derived anatomical data, and all-cause mortality. Univariate and multivariate logistic regressions determined which variables best predicted 1-year survival. Results One-year survival after EVAR was 93.7% (1,544/1,647) and 30-day survival was 98.4% (1,620/1,647). Univariate analyses found that nine preoperative variables were significantly associated with 1-year survival. Five variables were included in the final multivariate model: American Society of Anesthesiologists physical status, aneurysm diameter, creatinine, respiratory assessment, and severity of iliac artery calcification (receiver-operator curve 0.717, R2 =.117). Predicted 1-year survival ranged from 98.6% to 68.0%, based on differences in aneurysm size and patient comorbidities. Conclusion Personalised 1-year survival risk enables surgeons and patients to consider seriously the risks and benefits of EVAR prior to surgery.

AB - Objective/background The purpose of this study was to determine the preoperative variables that best predict 1-year survival following elective endovascular aneurysm repair (EVAR), a period of time that would suggest the patient had benefited from the procedure. Most EVAR survival studies focus on early and late survival; scant information is available for 1-year survival. Methods Data from two Australian audits of EVAR (1999-2001 and 2009-13) were combined (n = 1,647). Preoperative variables included routine demographic data, clinical health assessments, computed tomography-derived anatomical data, and all-cause mortality. Univariate and multivariate logistic regressions determined which variables best predicted 1-year survival. Results One-year survival after EVAR was 93.7% (1,544/1,647) and 30-day survival was 98.4% (1,620/1,647). Univariate analyses found that nine preoperative variables were significantly associated with 1-year survival. Five variables were included in the final multivariate model: American Society of Anesthesiologists physical status, aneurysm diameter, creatinine, respiratory assessment, and severity of iliac artery calcification (receiver-operator curve 0.717, R2 =.117). Predicted 1-year survival ranged from 98.6% to 68.0%, based on differences in aneurysm size and patient comorbidities. Conclusion Personalised 1-year survival risk enables surgeons and patients to consider seriously the risks and benefits of EVAR prior to surgery.

KW - Abdominal aortic aneurysm

KW - Mortality

KW - Endovascular procedures

UR - http://purl.org/au-research/grants/NHMRC/565335

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DO - 10.1016/j.ejvs.2015.12.019

M3 - Article

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EP - 534

JO - European Journal of Vascular and Endovascular Surgery

JF - European Journal of Vascular and Endovascular Surgery

SN - 1078-5884

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