Abstract
Background: Preeclampsia is a serious condition that is linked to poor perinatal outcomes. In Ethiopia, the overall prevalence of preeclampsia and its associated factors is uncertain. Therefore, the purpose of this review was to find the prevalence of pre-eclampsia and its determinants in Ethiopia.
Methods: To find primary studies, PubMed, Google Scholar, HINAR, Scopus, the Web of Sciences, and grey literature searches were used between January 1, 2013, and January 1, 2023, in Ethiopia. A Microsoft Excel sheet was used to extract data. The pooled prevalence of pre- eclampsia was predicted using a random-effect model.
Results: Twenty-nine studies were included. The pooled prevalence of pre-eclampsia was 11.51% (95% CI: 8.41, 14.61). Age > 35 years old (AOR = 2.34, 95%CI, 1.74–2.94; p-value = 0.64), housewife (AOR = 2.76, 95%CI, 1.2–4.32; p-value = 0.37), previous history of preeclampsia (AOR = 4.02, 95%CI, 2.91–5.55; p-value = 0.09), family history of hypertension (OR = 1.84, 95%CI, 1.39–2.3; p-value = 0.4), history of chronic hypertension (AOR = 2.44, 95%CI, 1.8–3.08; p-value = 0.67), history of multiple pregnancies (AOR = 1.45, 95%CI, 1.09–1.8; p-value = 0.38), and alcohol intake during pregnancy (AOR = 1.53, 95%CI, 1.03–2.04; p-value= 0.03) were the determinants of pre-eclampsia.
Conclusions: When compared to previous studies, the overall pooled prevalence of preeclampsia was high. Preeclampsia is associated with maternal age >35 years, being a housewife, having a history of preeclampsia, having a history of chronic hypertension, having a family history of hypertension, having diabetes mellitus, drinking alcohol during pregnancy, and having multiplepregnancies.
Methods: To find primary studies, PubMed, Google Scholar, HINAR, Scopus, the Web of Sciences, and grey literature searches were used between January 1, 2013, and January 1, 2023, in Ethiopia. A Microsoft Excel sheet was used to extract data. The pooled prevalence of pre- eclampsia was predicted using a random-effect model.
Results: Twenty-nine studies were included. The pooled prevalence of pre-eclampsia was 11.51% (95% CI: 8.41, 14.61). Age > 35 years old (AOR = 2.34, 95%CI, 1.74–2.94; p-value = 0.64), housewife (AOR = 2.76, 95%CI, 1.2–4.32; p-value = 0.37), previous history of preeclampsia (AOR = 4.02, 95%CI, 2.91–5.55; p-value = 0.09), family history of hypertension (OR = 1.84, 95%CI, 1.39–2.3; p-value = 0.4), history of chronic hypertension (AOR = 2.44, 95%CI, 1.8–3.08; p-value = 0.67), history of multiple pregnancies (AOR = 1.45, 95%CI, 1.09–1.8; p-value = 0.38), and alcohol intake during pregnancy (AOR = 1.53, 95%CI, 1.03–2.04; p-value= 0.03) were the determinants of pre-eclampsia.
Conclusions: When compared to previous studies, the overall pooled prevalence of preeclampsia was high. Preeclampsia is associated with maternal age >35 years, being a housewife, having a history of preeclampsia, having a history of chronic hypertension, having a family history of hypertension, having diabetes mellitus, drinking alcohol during pregnancy, and having multiplepregnancies.
| Original language | English |
|---|---|
| Article number | e0287038 |
| Pages (from-to) | e0287038 |
| Number of pages | 23 |
| Journal | PLoS One |
| Volume | 18 |
| Issue number | 11 |
| DOIs | |
| Publication status | Published - 14 Nov 2023 |
| Externally published | Yes |
Keywords
- Preclampsia
- Hypertensive disorders in pregnancy
- Meta-analysis
- Diabetes mellitus
- Pregnancy
- Alcohol consumption
- Amhara people
- Systematic review
