Pressure-Flow Analysis for the Assessment of Pediatric Oropharyngeal Dysphagia

Lara Ferris, Nathalie Rommel, Sebastian Doeltgen, Ingrid Scholten, Stamatiki Kritas, Rammy Abu-Assi, Lisa McCall, Grace Seiboth, Katie Lowe, David Moore, Jenny Faulks, Taher Omari

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    Abstract

    Objectives To determine which objective pressure-impedance measures of pharyngeal swallowing function correlated with clinically assessed severity of oropharyngeal dysphagia (OPD) symptoms. Study design Forty-five children with OPD and 34 control children without OPD were recruited and up to 5 liquid bolus swallows were recorded with a solid-state high-resolution manometry with impedance catheter. Individual measures of pharyngeal and upper esophageal sphincter (UES) function and a swallow risk index composite score were derived for each swallow, and averaged data for patients with OPD were compared with those of control children without OPD. Clinical severity of OPD symptoms and oral feeding competency was based on the validated Dysphagia Disorders Survey and Functional Oral Intake Scale. Results Those objective measures that were markers of UES relaxation, UES opening, and pharyngeal flow resistance differentiated patients with and without OPD symptoms. Patients demonstrating abnormally high pharyngeal intrabolus pressures and high UES resistance, markers of outflow obstruction, were most likely to have signs and symptoms of overt Dysphagia Disorders Survey (OR 9.24, P = .05, and 9.7, P = .016, respectively). Conclusion Pharyngeal motor patterns can be recorded in children by the use of HRIM and pharyngeal function can be defined objectively with the use of pressure-impedance measures. Objective measurements suggest that pharyngeal dysfunction is common in children with clinical signs of OPD. A key finding of this study was evidence of markers of restricted UES opening.

    Original languageEnglish
    Pages (from-to)279-285.e1
    Number of pages8
    JournalJournal of Pediatrics
    Volume177
    DOIs
    Publication statusPublished - 2016

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    Ferris, L., Rommel, N., Doeltgen, S., Scholten, I., Kritas, S., Abu-Assi, R., McCall, L., Seiboth, G., Lowe, K., Moore, D., Faulks, J., & Omari, T. (2016). Pressure-Flow Analysis for the Assessment of Pediatric Oropharyngeal Dysphagia. Journal of Pediatrics, 177, 279-285.e1. https://doi.org/10.1016/j.jpeds.2016.06.032