TY - JOUR
T1 - Prevalence of depression in people with tuberculosis in East Africa
T2 - a systematic review and meta-analysis
AU - Alemu, Wondale Getinet
AU - Zeleke, Tadele Amare
PY - 2023/4/6
Y1 - 2023/4/6
N2 - Background: Depression is one of the most common mental health problems comorbid with tuberculosis. However, a consolidated picture of the prevalence of depression among tuberculosis patients in East Africa remains unknown. This systematic review and meta-analysis provide new understandings by systematically examining evidence concerning the prevalence of depression among tuberculosis patients in East Africa. Methods: Literature was found in a database of HINARI, SCOPUS, PubMed, Science Direct, and Google Scholar. The New-castle-Ottawa quality assessment scale was used to appraise the quality of the selected studies. Then, the DerSimonian and Laird random-effects model was applied because of the presence of heterogeneity among studies. Results: A total of 409 studies were accessed. However, only 29 qualified for a full-text review, and 9 studies with a population of 2838 were included in the qualitative description and quantitative analysis. The pooled prevalence estimate of depression amongst tuberculosis patients was 43.03 % (34.93, 51.13). The highest prevalence was observed in Kenya, with 45.71% (29.26, 62.16); a similar rate was observed in Ethiopia, with 45.11 % (34.60, 55.62). Subgroup analysis based on screening tool was used: 45.71% with BDI and 41.53% with PHQ.
AB - Background: Depression is one of the most common mental health problems comorbid with tuberculosis. However, a consolidated picture of the prevalence of depression among tuberculosis patients in East Africa remains unknown. This systematic review and meta-analysis provide new understandings by systematically examining evidence concerning the prevalence of depression among tuberculosis patients in East Africa. Methods: Literature was found in a database of HINARI, SCOPUS, PubMed, Science Direct, and Google Scholar. The New-castle-Ottawa quality assessment scale was used to appraise the quality of the selected studies. Then, the DerSimonian and Laird random-effects model was applied because of the presence of heterogeneity among studies. Results: A total of 409 studies were accessed. However, only 29 qualified for a full-text review, and 9 studies with a population of 2838 were included in the qualitative description and quantitative analysis. The pooled prevalence estimate of depression amongst tuberculosis patients was 43.03 % (34.93, 51.13). The highest prevalence was observed in Kenya, with 45.71% (29.26, 62.16); a similar rate was observed in Ethiopia, with 45.11 % (34.60, 55.62). Subgroup analysis based on screening tool was used: 45.71% with BDI and 41.53% with PHQ.
KW - Depression
KW - East Africa
KW - meta-analysis
KW - systematic review
KW - TB patients
UR - http://www.scopus.com/inward/record.url?scp=85156139752&partnerID=8YFLogxK
U2 - 10.4314/ahs.v23i1.25
DO - 10.4314/ahs.v23i1.25
M3 - Article
C2 - 37545972
AN - SCOPUS:85156139752
SN - 1680-6905
VL - 23
SP - 231
EP - 240
JO - African Health Sciences
JF - African Health Sciences
IS - 1
ER -
