Prevention and Treatment of Peritoneal Dialysis-Related Infections

Giovanni Strippoli, Kathryn Wiggins, David Johnson, Sankar Navaneethan, Giovanni Cancarini, Jonathan Craig

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Citations (Scopus)

Abstract

Peritoneal dialysis (PD) is an effective and widely used form of renalreplacement therapy and accounts for 15–50% of renal replace-ment therapy for patients with end-stage renal disease (ESRD).The longevity of PD and its broader uptake are reduced by the risk of PD-related infections [1]. The overall incidence of peritonitisis about one episode for every 19 patient months on PD [2], al-though this figure ranges from 1 in every 9.1 to 1 in every 27.9patient– months [3–5]. Peritonitis tends to be recurrent, with a very high rate of relapse (approximately 0.5 episodes/patient/year)[6]. Risk factors for developing peritonitis include advancing age [7,8], some ethnic groups [9,10], comorbidities such as diabetes and obesity [11], tropical climates [12,13], depression [14], nasal carriage of Staphylococcus aureus[15,16], and presence of exit site infections. Catheter design, implantation technique, and connection methodology also modulate the risk of peritonitis. It is unclearwhether PD modality (continuous ambulatory PD [CAPD] or automated PD [APD]) affects peritonitis rates [17,18].
Original languageEnglish
Title of host publicationEvidence-Based Nephrology
PublisherJohn Wiley and Sons Inc.
Chapter47
Pages509-532
Number of pages24
Edition1
ISBN (Electronic)9781444303391
ISBN (Print)9781405139755
DOIs
Publication statusPublished - 2009

Fingerprint Dive into the research topics of 'Prevention and Treatment of Peritoneal Dialysis-Related Infections'. Together they form a unique fingerprint.

  • Cite this

    Strippoli, G., Wiggins, K., Johnson, D., Navaneethan, S., Cancarini, G., & Craig, J. (2009). Prevention and Treatment of Peritoneal Dialysis-Related Infections. In Evidence-Based Nephrology (1 ed., pp. 509-532). John Wiley and Sons Inc.. https://doi.org/10.1002/9781444303391.ch47