Primary sclerosing cholangitis: A rare cause of liver dysfunction in pregnancy

Laura Slade, Linda McKendrick, Rosalie Grivell

Research output: Contribution to journalArticlepeer-review


Primary sclerosing cholangitis is an uncommon condition with few cases reported in pregnancy. We present the case and outcome of a 28-year-old female presenting in her second pregnancy with new onset liver dysfunction, eventually diagnosed with primary sclerosing cholangitis. She went into spontaneous preterm labour and delivered a healthy infant but has subsequently continued to deteriorate and underwent a liver transplant 11 months post-delivery.

Original languageEnglish
Number of pages3
JournalObstetric Medicine
Early online date9 Mar 2021
Publication statusE-pub ahead of print - 9 Mar 2021


  • Puerperal disorders
  • liver dysfunction in pregnancy
  • Primary sclerosing cholangitis
  • new onset liver dysfunction
  • spontaneous preterm labour


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