Abstract
Background/Purpose: Programmed death protein 1 (PD-1) expressing T cells, including T follicular and T peripheral helper cells, are expanded in the circulation of individuals with rheumatoid arthritis (RA). Despite this, the origins of these cells and their functional role in RA remain poorly understood. To address this, we sought to investigate the genetic profiles of PD-1-expressing lymphocytes of the peripheral blood and synovial infiltrate of patients with early RA, and to characterise these cells in disease.
Original language | English |
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Number of pages | 2 |
Publication status | Published - 2021 |
Event | American College of Rheumatology Convergence 2021 - Virtual, United States Duration: 5 Nov 2021 → 9 Nov 2021 |
Conference
Conference | American College of Rheumatology Convergence 2021 |
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Abbreviated title | ACR Convergence 2021 |
Country/Territory | United States |
Period | 5/11/21 → 9/11/21 |
Keywords
- Rheumatoid arthritis
- Programmed cell death
- Treatments