Prolonged remission of chronic reactive arthritis treated with three infusions of infliximab

Mihir Wechalekar, Maureen Rischmueller, Samuel Whittle, Simon Burnet, Catherine Hill

    Research output: Contribution to journalArticle

    13 Citations (Scopus)

    Abstract

    Reactive arthritis is generally self-remitting but can be chronic. Predictors of chronicity include HLA B27 positivity and triggering infections with Yersinia, Salmonella, Shigella, or Chlamydia. Nonsteroidal antiinflammatory drugs and local steroids are the mainstays, with some evidence for disease modifying antirheumatic drugs. Limited evidence suggests effectiveness of tumor necrosis factor antagonists. We report the case of reactive arthritis following a Chlamydia urinary tract infection progressing to a chronic course, treated with a short course of high dose tumor necrosis factor antagonist, followed up for over 2 years with prolonged remission, allowing discontinuation of disease modifying antirheumatic drug therapy.

    Original languageEnglish
    Pages (from-to)79-80
    Number of pages2
    JournalJCR-JOURNAL OF CLINICAL RHEUMATOLOGY
    Volume16
    Issue number2
    DOIs
    Publication statusPublished - Mar 2010

    Keywords

    • Reactive arthritis
    • TNF antagonists

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