TY - JOUR
T1 - Psychiatric comorbidity in people with epilepsy in Ethiopia
T2 - Systematic review and meta-analysis
AU - Tinsae, Techilo
AU - Shumet, Shegaye
AU - Melkam, Mamaru
AU - Segon, Tesfaye
AU - Medfu Takelle, Girmaw
AU - Rtbey, Gidey
AU - Nakie, Girum
AU - Fentahun, Setegn
AU - Andualem, Fantahun
AU - Getinet, Wondale
PY - 2024/3
Y1 - 2024/3
N2 - Background: Psychiatric comorbidity is a double burden among people with epilepsy. Since people with epilepsy are more vulnerable to psychiatric illnesses. So, the implementation of an appropriate intervention to minimize the double burden of comorbidity is very important. Therefore, this systematic review and meta-analysis aimed to assess the prevalence and associated factors of psychiatric comorbidity among people with epilepsy in Ethiopia. Methods: This systematic review and meta-analysis followed the Preferred Reporting Item Review and Meta-analysis (PRISMA) guideline. Searching databases were PubMed, PsycINFO, Web of Science, Cochrane Library, Google Scholar, and HINARI. The quality of the included articles was assessed using the Newcastle-Ottawa Scale (NOS). The pooled meta-logistic regression was computed to estimate the pooled prevalence and the risk factors with a 95% CI. Results: The pooled prevalence of psychiatric comorbidity in people with epilepsy was 34.69 % (95 % CI: 29.27, 40.10). Frequent seizures (POR = 2.94: 95 % CI: 1.08, 8.00) and a history of divorce (POR = 2.00: 95 % CI: 1.09, 3.81) were associated factors of psychiatric comorbidity in people with epilepsy. Conclusions: This systematic review and meta-analysis revealed that the pooled prevalence of psychiatric comorbidity among people with epilepsy was found to be higher compared with the general population. Therefore, among people with epilepsy, parallel psychiatric evaluation is very important along with neurological evaluation.
AB - Background: Psychiatric comorbidity is a double burden among people with epilepsy. Since people with epilepsy are more vulnerable to psychiatric illnesses. So, the implementation of an appropriate intervention to minimize the double burden of comorbidity is very important. Therefore, this systematic review and meta-analysis aimed to assess the prevalence and associated factors of psychiatric comorbidity among people with epilepsy in Ethiopia. Methods: This systematic review and meta-analysis followed the Preferred Reporting Item Review and Meta-analysis (PRISMA) guideline. Searching databases were PubMed, PsycINFO, Web of Science, Cochrane Library, Google Scholar, and HINARI. The quality of the included articles was assessed using the Newcastle-Ottawa Scale (NOS). The pooled meta-logistic regression was computed to estimate the pooled prevalence and the risk factors with a 95% CI. Results: The pooled prevalence of psychiatric comorbidity in people with epilepsy was 34.69 % (95 % CI: 29.27, 40.10). Frequent seizures (POR = 2.94: 95 % CI: 1.08, 8.00) and a history of divorce (POR = 2.00: 95 % CI: 1.09, 3.81) were associated factors of psychiatric comorbidity in people with epilepsy. Conclusions: This systematic review and meta-analysis revealed that the pooled prevalence of psychiatric comorbidity among people with epilepsy was found to be higher compared with the general population. Therefore, among people with epilepsy, parallel psychiatric evaluation is very important along with neurological evaluation.
KW - Anxiety
KW - Depression
KW - Epilepsy
KW - Psychiatric comorbidity
KW - Psychological distress
UR - http://www.scopus.com/inward/record.url?scp=85185161658&partnerID=8YFLogxK
U2 - 10.1016/j.yebeh.2024.109648
DO - 10.1016/j.yebeh.2024.109648
M3 - Review article
C2 - 38277847
AN - SCOPUS:85185161658
SN - 1525-5050
VL - 152
JO - Epilepsy and Behavior
JF - Epilepsy and Behavior
M1 - 109648
ER -