Pullout strength of cancellous screws in human femoral heads depends on applied insertion torque, trabecular bone microarchitecture and areal bone mineral density

Rosidah Ab-Lazid, Egon Perilli, Melissa Ryan, John Costi, Karen Reynolds

    Research output: Contribution to journalArticle

    8 Citations (Scopus)

    Abstract

    For cancellous bone screws, the respective roles of the applied insertion torque (T Insert) and of the quality of the host bone (microarchitecture, areal bone mineral density (aBMD)), in contributing to the mechanical holding strength of the bone-screw construct (F Pullout), are still unclear. During orthopaedic surgery screws are tightened, typically manually, until adequate compression is attained, depending on surgeons' manual feel. This corresponds to a subjective insertion torque control, and can lead to variable levels of tightening, including screw stripping. The aim of this study, performed on cancellous screws inserted in human femoral heads, was to investigate which, among the measurements of aBMD, bone microarchitecture, and the applied T Insert, has the strongest correlation with F Pullout.Forty six femoral heads were obtained, over which microarchitecture and aBMD were evaluated using micro-computed tomography and dual X-ray absorptiometry. Using an automated micro-mechanical test device, a cancellous screw was inserted in the femoral heads at T Insert set to 55% to 99% of the predicted stripping torque beyond screw head contact, after which F Pullout was measured. F Pullout exhibited strongest correlations with T Insert (R=0.88, p<0.001), followed by structure model index (SMI, R=-0.81, p<0.001), bone volume fraction (BV/TV, R=0.73, p<0.001) and aBMD (R=0.66, p<0.01). Combinations of T Insert with microarchitectural parameters and/or aBMD did not improve the prediction of F Pullout.These results indicate that, for cancellous screws, F Pullout depends most strongly on the applied T Insert, followed by microarchitecture and aBMD of the host bone. In trabecular bone, screw tightening increases the holding strength of the screw-bone construct.

    Original languageEnglish
    Pages (from-to)354-361
    Number of pages8
    JournalJournal of the Mechanical Behavior of Biomedical Materials
    Volume40
    Issue numberDec
    DOIs
    Publication statusPublished - 2014

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