Pulmonary Congestion and Left Ventricular Dysfunction after Myocardial Infarction: Insights from the PARADISE-MI Trial

Mark C. Petrie, Jean L. Rouleau, Brian Claggett, Karola Jering, Peter Van Der Meer, Lars Køber, Zi Michael Miao, Eldrin Lewis, Christopher Granger, Carmine G. De Pasqulae, Douglas Mann, Philippe Gabriel Steg, Aldo Maggioni, Offer Amir, Marty Lefkowitz, Eugene Braunwald, Scott D. Solomon, John J.V. McMurray, Marc A. Pfeffer

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

The PARADISE-MI ([Prospective ARNI vs ACE Inhibitors Trial to Determine Superiority in Reducing Heart Failure Events After MI] URL: https://clinicaltrials.gov; Unique identifier: NCT02924727) trial investigated whether sacubitril/valsartan improved outcomes compared to ramipril after acute myocardial infarction (MI).1 Sacubitril/valsartan did not reduce the risk of the primary composite outcome of cardiovascular death, outpatient development of heart failure (HF), or hospitalization for HF compared to ramipril.
Original languageEnglish
Pages (from-to)335-338
Number of pages4
JournalCirculation
Volume149
Issue number4
DOIs
Publication statusPublished - 23 Jan 2024

Keywords

  • heart failure
  • myocardial infarction
  • ramipril
  • valsartan
  • ventricular dysfunction, left

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