Quality control: Another player joins the ERAD cast

John Michael Lord; Lynne M. Roberts; Colin J. Stirling

doi:10.1016/j.cub.2005.11.013

Quality control: Another player joins the ERAD cast

John Michael Lord
, Lynne M. Roberts
, Colin J. Stirling

President and Vice-Chancellor

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Abstract

The quality control system known as ERAD removes misfolded proteins from the ER to the cytosol for degradation. The AAA ATPase Cdc48p and ubiquitin ligases play crucial roles; their relationship has been unclear, but recent work has shown that the membrane protein Ubx2p links their functions in yeast.

Original language	English
Pages (from-to)	R963-R964
Number of pages	2
Journal	Current Biology
Volume	15
Issue number	23
DOIs	https://doi.org/10.1016/j.cub.2005.11.013
Publication status	Published - 2005

Access to Document

10.1016/j.cub.2005.11.013Licence: Other

Cite this

@article{8c6672e4ef054822bd05c32aa1b30a8f,

title = "Quality control: Another player joins the ERAD cast",

abstract = "The quality control system known as ERAD removes misfolded proteins from the ER to the cytosol for degradation. The AAA ATPase Cdc48p and ubiquitin ligases play crucial roles; their relationship has been unclear, but recent work has shown that the membrane protein Ubx2p links their functions in yeast.",

author = "Lord, \{John Michael\} and Roberts, \{Lynne M.\} and Stirling, \{Colin J.\}",

year = "2005",

doi = "10.1016/j.cub.2005.11.013",

language = "English",

volume = "15",

pages = "R963--R964",

journal = "Current Biology",

issn = "0960-9822",

publisher = "Cell Press",

number = "23",

}

TY - JOUR

T1 - Quality control: Another player joins the ERAD cast

AU - Lord, John Michael

AU - Roberts, Lynne M.

AU - Stirling, Colin J.

PY - 2005

Y1 - 2005

N2 - The quality control system known as ERAD removes misfolded proteins from the ER to the cytosol for degradation. The AAA ATPase Cdc48p and ubiquitin ligases play crucial roles; their relationship has been unclear, but recent work has shown that the membrane protein Ubx2p links their functions in yeast.

AB - The quality control system known as ERAD removes misfolded proteins from the ER to the cytosol for degradation. The AAA ATPase Cdc48p and ubiquitin ligases play crucial roles; their relationship has been unclear, but recent work has shown that the membrane protein Ubx2p links their functions in yeast.

U2 - 10.1016/j.cub.2005.11.013

DO - 10.1016/j.cub.2005.11.013

M3 - Article

SN - 0960-9822

VL - 15

SP - R963-R964

JO - Current Biology

JF - Current Biology

IS - 23

ER -

Quality control: Another player joins the ERAD cast

Abstract

Access to Document

Fingerprint

Cite this