Quality Indicators and Benchmarks for Guideline-Recommended Fecal Occult Blood Tests

James E. Allison, Callum G. Fraser, Stephen P. Halloran, Graeme P. Young

    Research output: Chapter in Book/Report/Conference proceedingChapter


    The fecal immunochemical test (FIT) for hemoglobin is beginning to be accepted as a legitimate and attractive choice for use as a screening test for colorectal cancer in the USA, but, as yet, many primary care physicians, gastroenterologists, health policy experts, and US laboratory professionals remain unfamiliar with FIT’s usefulness and potential or do not understand why quality standards and benchmarks are critical to FIT effectiveness and for their evaluation. All such stakeholders must understand the need for FIT refinement and standardization to ensure traceability of analytical results, consistency in fecal sample mass evaluation, assessment of hemoglobin (Hb) stability, and common units for reporting Hb concentrations. We hope this chapter will help provide the reader with an understanding of the importance of adopting a standardized approach to FIT nomenclature, to the measurement of fecal Hb (f-Hb) concentrations, and of how FIT results are reported.
    Original languageEnglish
    Title of host publicationColorectal Cancer Screening
    Subtitle of host publicationQuality and Benchmarks
    EditorsAasma Shaukat, John L. Allen
    Number of pages15
    ISBN (Electronic)9781493923335
    ISBN (Print)9781493923328
    Publication statusPublished - 15 Mar 2015


    • Colorectal cancer (CRC)
    • Colorectal cancer screening
    • Fecal immunochemical test for hemoglobin
    • Fecal occult blood test
    • Population screening


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