Radiation sensitivity of human malignant lymphocytes

R. Seshadri, C. Matthews, A. A. Morley

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)


A simple and rapid in vitro technique to assess the sensitivity of human malignant lymphocytes to roentgen irradiation is described. A variety of established malignant lymphocyte cell lines were cloned in microwells and clone survival was used as the end-point. The survival of the clonogenic malignant lymphocyte down to a fraction of approximately 0.001 could be measured accurately. Except for a T-cell line, the radiation sensitivities of the cell lines were similar to that of normal T-lymphocytes.

Original languageEnglish
Pages (from-to)411-414
Number of pages4
JournalActa Oncologica
Issue number5
Publication statusPublished - 1985
Externally publishedYes


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