Raman Spectroscopy

Keith C. Gordon, Sara J. Fraser-Miller

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

This chapter describes how Raman spectroscopy may be used in the analysis of pharmaceutical problems. The basic ideas around the technique are discussed along with some of the key issues in measuring Raman spectra that may be relevant to pharmaceutical samples. The limitations and strengths of different instruments (dispersive and Fourier-transform) are described. The use of Raman spectroscopy is highlighted in a number of case studies that utilize multivariate techniques; polymorphism, drug delivery and counterfeit drug studies are described. Finally, new technologies that are set to further enhance Raman spectroscopy as a method for analysis, such as low frequency Raman, spatially offset Raman scattering, transmission Raman and spatial heterodyne Raman spectroscopy are discussed.
Original languageEnglish
Title of host publicationAnalytical Techniques in the Pharmaceutical Sciences
EditorsAnette Müllertz, Yvonne Perrie, Thomas Rades
Place of PublicationNew York
PublisherSpringer New York LLC
Chapter4
Pages139-169
Number of pages31
ISBN (Electronic)9781493940295
ISBN (Print)9781493940271
DOIs
Publication statusPublished - 2016
Externally publishedYes

Publication series

NameAdvances in Delivery Science and Technology
PublisherSpringer
ISSN (Print)2192-6204
ISSN (Electronic)2192-6212

Keywords

  • Raman
  • Chemometrics
  • Polymorphism
  • Drug delivery
  • Counterfeit medicines
  • Low frequency Raman sp

Fingerprint

Dive into the research topics of 'Raman Spectroscopy'. Together they form a unique fingerprint.

Cite this