Rationale, design, and progress of the ENhanced Control of Hypertension ANd Thrombolysis strokE stuDy (ENCHANTED) trial: An international multicenter 2×2 quasi-factorial randomized controlled trial of low- vs. standard-dose rt-PA and early intensive vs. guideline-recommended blood pressure lowering in patients with acute ischaemic stroke eligible for thrombolysis treatment

For the ENCHANTED investigators, Yining Huang, Vijay K. Sharma, Thompson Robinson, Richard I. Lindley, Xiaoying Chen, Jong Sung Kim, Pablo Lavados, Verónica Olavarría, Hisatomi Arima, Sully Fuentes, Huy Thang Nguyen, Tsong Hai Lee, Mark W. Parsons, Christopher Levi, Andrew M. Demchuk, Philip M.W. Bath, Joseph P. Broderick, Geoffrey A. Donnan, Sheila MartinsOctavio M. Pontes-Neto, Federico Silva, Jeyaraj Pandian, Stefano Ricci, Christian Stapf, Mark Woodward, Jiguang Wang, John Chalmers, Craig S. Anderson

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