Re-evaluation of dietary interventions in rheumatoid arthritis: can we improve patient conversations around food choices?

Prakriti Sharma, Shannon Brown, Elke M. Sokoya

Research output: Contribution to journalReview articlepeer-review

1 Citation (Scopus)
33 Downloads (Pure)

Abstract

Rheumatoid arthritis (RA) is one of over 100 different types of autoimmune conditions. In RA, the cells of the immune system attack the tissue lining the joints, triggering inflammation. A large body of research suggests that the underlying trigger(s) of RA are unique to an individual. For example, increased risk of RA can be driven by smoking tobacco in one individual and mercury exposure in another. Due to the development of next-generation sequencing technology, the critical role of the microbiota in shaping RA risk has been elucidated. Therefore, it is surprising that diet, arguably the most important lever in shaping the gut microbiota, is ineffective in the treatment of RA, even in a sub-set of patients. To attempt to rationalise this apparent paradox, we conducted an umbrella review to address the question as to whether diet can affect outcomes in RA.
Original languageEnglish
Pages (from-to)1409-1419
Number of pages11
JournalRheumatology International
Volume44
Issue number8
Early online date20 Feb 2024
DOIs
Publication statusE-pub ahead of print - 20 Feb 2024

Keywords

  • Autoimmune
  • Diet
  • Fasting
  • Food sensitivity
  • Rheumatoid arthritis

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