Recent advances in the synthesis of pyrroles via multicomponent reactions using arylglyoxals

Ramin Javahershenas, Fatemeh Majidi Arlan, Rolf Herman Prager, Jabbar Khalafy

    Research output: Contribution to journalReview articlepeer-review

    6 Citations (Scopus)
    17 Downloads (Pure)

    Abstract

    Pyrrole is widely known as an active pharmacophore. This core framework plays an important role in several natural and biological products. Due to its properties, developing such scaffolds has attracted much attention. The accessibility of these role-playing heterocyclic motifs via easy, high efficiency and developed methodologies is of interest and value in the creation of new heterocyclic compounds. This review highlights the broad range of applications of arylglyoxals in the synthesis of pyrrole derivatives via multicomponent reactions over the period 2010-2019.

    Original languageEnglish
    Pages (from-to)117-152
    Number of pages36
    JournalArkivoc
    Volume2020
    Issue number1
    DOIs
    Publication statusPublished - 4 May 2020

    Keywords

    • Arylglyoxals
    • Multicomponent reactions
    • Pyrroles

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