Recording In Vivo Human Colonic Motility: What Have We Learnt Over the Past 100 Years?

    Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

    7 Citations (Scopus)

    Abstract

    To understand the abnormalities that underpin functional gut disorders we must first gain insight into the normal patterns of gut motility. While detailed information continually builds on the motor patterns (and mechanisms that control them) of the human esophagus and anorectum, our knowledge of normal and abnormal motility in the more inaccessible regions of the gut remains poor. This particularly true of the human colon. Investigation of in vivo colonic motor patterns is achieved through measures of transit (radiology, scintigraphy and, more recently, “smart pills”) or by direct real-time recording of colonic contractility (intraluminal manometry). This short review will provide an overview of findings from the past and present and attempt to piece together the complex nature of colonic motor patterns. In doing so it will build a profile of human colonic motility and determine the likely mechanisms that control this motility.

    Original languageEnglish
    Title of host publicationThe Enteric Nervous System: 30 Years Later
    PublisherSpringer
    Pages213-222
    Number of pages10
    Volume891
    ISBN (Print)9783319275925
    DOIs
    Publication statusPublished - 2016

    Publication series

    NameAdvances in Experimental Medicine and Biology
    Volume891
    ISSN (Print)0065-2598
    ISSN (Electronic)2214-8019

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