Hemophagocytic lymphohistiocytosis (HLH) is a potentially fatal hyper-inflammatory disease induced by aberrant immune activation and subsequent proliferation of macrophages, histiocytes and T-helper cells. In this abstract we present a case of HLH, which relapsed twice despite ongoing treatment, and we hypothesize on possible causes and mechanisms...
- Hemophagocytic Lymphohistiocytosis
- hyper-inflammatory disease
- aberrant immune activation
- Myeloid Gene Mutation