Abstract
The association between red blood cell (RBC) auto-and alloantibodies has been reported, primarily in the context of warm autoimmune hemolytic anemia (AIHA). Forty to fifty percent of AIHA patients also have RBC-alloantibodies,21 usually as a result of previous RBC transfusions, with autoantibodies playing very little role in their development. Conversely, the occurrence of autoantibody in alloimmunized patients is less well recognized and has primarily been reported in sickle cell disease (SCD) and thalassemia.63 Importantly, autoimmunization can lead to severe AIHA754 and make it difficult to find compatible blood. However, incidence, risk factors, and significance of RBC autoimmunization has not been reported in myelodysplastic syndrome (MDS) patients...
Original language | English |
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Pages (from-to) | E451-E454 |
Number of pages | 4 |
Journal | Haematologica |
Volume | 104 |
Issue number | 10 |
DOIs | |
Publication status | Published - 1 Oct 2019 |
Keywords
- Myelodysplastic syndromes
- autoimmunization