Regeneration of magnetic nanoparticles used in the removal of pathogenesis-related proteins from white wines

Agnieszka Mierczynska-Vasilev, Geridi Qi, Paul Smith, Keren Bindon, Krasimir Vasilev

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)
26 Downloads (Pure)


Protein haze remains a serious problem for the wine industry and requires costly bentonite treatment, leading to significant wine volume loss. Recently developed magnetic separation technology that allows a fast and efficient separation of haze proteins from wine shows promise for the development of an alternative method for white wine fining. The key purpose of this study was to understand the potential of the nanoparticles to be reused in multiple fining and regeneration cycles. Bare and acrylic-acid-based plasma polymer coated magnetic nanoparticles were cleaned with water, 10% SDS/water and acetone/water solution after each adsorption cycle to investigate their restored efficiency in removing pathogenesis-related proteins from three unfined white wines. The concentrations of metals, acids and phenolics were monitored to determine changes in the concentration of these essential wine constituents. The regeneration study verified that the acrylic acid plasma-coated magnetic nanoparticles, which underwent ten successive adsorption-desorption processes, still retained close to the original removal capacity for haze proteins from wines when 10% SDS solution and water were used for surface regeneration. In addition, the concentrations of organic acids and wine phenolic content remained almost unchanged, which are important indicators for the retention of the original wine composition.

Original languageEnglish
Article number1
Number of pages13
Issue number1
Publication statusPublished - Jan 2020
Externally publishedYes


  • Magnetic nanoparticles
  • Pathogenesis-related proteins
  • Protein removal
  • Regeneration
  • White wine


Dive into the research topics of 'Regeneration of magnetic nanoparticles used in the removal of pathogenesis-related proteins from white wines'. Together they form a unique fingerprint.

Cite this