Relationships between changes in symptom ratings, neuropsychological test performance and quality of life in schizophrenic patients treated with clozapine

Cherrie A. Galletly; C. Richard Clark; Alexander C. McFarlane; Darren L. Weber

doi:10.1016/S0165-1781(97)00062-0

Relationships between changes in symptom ratings, neuropsychological test performance and quality of life in schizophrenic patients treated with clozapine

Cherrie A. Galletly, C. Richard Clark, Alexander C. McFarlane, Darren L. Weber

Research output: Contribution to journal › Article › peer-review

108 Citations (Scopus)

Abstract

This study examined the correlations between reduction in symptoms, changes in neuropsychological test performance and improved quality of life in 19 schizophrenic outpatients treated with clozapine. Reduction in both negative symptoms and general psychopathology was associated with a better quality of life. Some improvement in neuropsychological test performance was found, with a variable pattern of association with change in psychopathology. Improved verbal fluency was associated with reduction in negative symptoms, while improved verbal concept formation was associated with reduction in positive symptoms.

Original language	English
Pages (from-to)	161-166
Number of pages	6
Journal	Psychiatry Research
Volume	72
Issue number	3
DOIs	https://doi.org/10.1016/S0165-1781(97)00062-0
Publication status	Published - 10 Oct 1997

Keywords

Cognition
Negative symptoms
Positive symptoms

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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AU - Weber, Darren L.

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AB - This study examined the correlations between reduction in symptoms, changes in neuropsychological test performance and improved quality of life in 19 schizophrenic outpatients treated with clozapine. Reduction in both negative symptoms and general psychopathology was associated with a better quality of life. Some improvement in neuropsychological test performance was found, with a variable pattern of association with change in psychopathology. Improved verbal fluency was associated with reduction in negative symptoms, while improved verbal concept formation was associated with reduction in positive symptoms.

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KW - Positive symptoms

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Relationships between changes in symptom ratings, neuropsychological test performance and quality of life in schizophrenic patients treated with clozapine

Abstract

Keywords

UN SDGs

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