Reliability and Accuracy of Six Hand-Held Blood Lactate Analysers

Jacinta Bonaventura, Ken Sharpe, Emma Knight, Kate Fuller, Rebecca Tanner, Christopher Gore

    Research output: Contribution to journalArticlepeer-review

    54 Citations (Scopus)

    Abstract

    The reliability and accuracy of five portable blood lactate (BLa) analysers (Lactate Pro, Lactate Pro2, Lactate Scout+, Xpress™, and Edge) and one handheld point-of-care analyser (i-STAT) were compared to a criterion (Radiometer ABL90). Two devices of each brand of analyser were assessed using 22 x 6 mL blood samples taken from five subjects at rest and during exercise who generated lactate ranging ~1-23 mM. Each sample was meas-ured simultaneously ~6 times on each device. Reliability was assessed as the within-sample standard deviation (wsSD) of the six replicates; accuracy as the bias compared with the ABL90; and overall error (the root mean squared error (√MSE)) was calculated as the square root of (wsSD 2 and bias 2 ). The √MSE indicated that both the Edge and Xpress had low total error (~0-2 mM) for lactate concentrations <15 mM, whereas the Edge and Lactate Pro2 were the better of the portable analysers for concentrations >15 mM. In all cases, bias (negative) was the major contribution to the √MSE. In conclusion, in a clinical setting where BLa is generally <15 mM the Edge and Xpress devices are relevant, but for athlete testing where peak BLa is important for training prescription the Edge and Lactate Pro2 are preferred.

    Original languageEnglish
    Pages (from-to)203-214
    Number of pages12
    JournalJournal of Sports Science and Medicine
    Volume14
    Issue number1
    Publication statusPublished - 2014

    Keywords

    • Analytical performance
    • Bias
    • Precision
    • Root mean squared error

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