Remote Monitoring Alert Burden: An Analysis of Transmission in >26,000 Patients

Catherine J. O'Shea, Melissa E. Middeldorp, Jeroen M. Hendriks, Anthony G. Brooks, Dennis H. Lau, Mehrdad Emami, Ricardo Mishima, Anand Thiyagarajah, Suzanne Feigofsky, Rakesh Gopinathannair, Niraj Varma, Kevin Campbell, Prashanthan Sanders

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)


Objectives: This study sought to determine the remote monitoring (RM) alert burden in a multicenter cohort of patients with a cardiac implantable electronic device (CIED). Background: RM of CIEDs allows timely recognition of patient and device events requiring intervention. Most RM involves burdensome manual workflow occurring exclusively on weekdays during office hours. Automated software may reduce such a burden, streamlining real-time alert responses. Methods: We retrospectively analyzed 26,713 consecutive patients with a CIED undergoing managed RM utilizing PaceMate software between November 2018 and November 2019. Alerts were analyzed according to type, acuity (red indicates urgent, and yellow indicates nonurgent) and CIED category. Results: In total, 12,473 (46.7%) patients had a permanent pacemaker (PPM), 9,208 (34.5%) had an implantable cardioverter-defibrillator (ICD), and 5,032 (18.8%) had an implantable loop recorder (ILR). Overall, 82,797 of the 205,804 RM transmissions were alerts, with the remainder being scheduled transmissions. A total of 14,638 (54.8%) patients transmitted at least 1 alert. Permanent pacemakers were responsible for 25,700 (31.0%) alerts, ICDs for 15,643 (18.9%) alerts, and ILRs for 41,454 (50.1%) alerts, with 3,935 (4.8%) red alerts and 78,862 (95.2%) yellow alerts. ICDs transmitted 2,073 (52.7%) red alerts; 5,024 (32.1%) ICD alerts were for ventricular tachyarrhythmias and antitachycardia pacing/shock delivery. Conclusions: In an RM cohort of 26,713 patients with CIEDs, 54.8% of patients transmitted at least 1 alert during a 12-month period, totaling over 82,000 alerts. ILRs were overrepresented, and ICDs were underrepresented, in these alerts. The enormity of the number of transmissions and the growing ILR alert burden highlight the need for new management pathways for RM.

Original languageEnglish
Pages (from-to)226-234
Number of pages9
JournalJACC: Clinical Electrophysiology
Issue number2
Early online date25 Nov 2020
Publication statusPublished - Feb 2021


  • cardiac resynchronization therapy
  • home monitoring
  • implantable cardioverter-defibrillator
  • implantable loop recorder
  • pacemaker
  • remote transmissions


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