Reply to Martinez-Garcia et al. and to Abreu and Punjabi

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We thank Dr. Martinez-Garcia and colleagues, as well as Drs. Abreu and Punjabi, for their positive comments and thoughtful insights on our recent research on multinight prevalence and the potential impact of night-to-night variability in obstructive sleep apnea (OSA)severity on misdiagnosis (1). Some of the clinically relevant discussion points raised have been eloquently outlined in the accompanying editorial by Dr. Simonds (2). To provide further insights on this important topic as outlined in the letters to the editor, additional commentary and key analyses are provided below.
Original languageEnglish
Pages (from-to)126-129
Number of pages4
JournalAmerican Journal of Respiratory and Critical Care Medicine
Issue number1
Publication statusPublished - 1 Jul 2022


  • Obstructive sleep apnea (OSA)
  • Apnea-hypopnea index
  • Misdiagnosis
  • clinical decision making

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