Re-entry to their country of origin is a significant disruption for a number of sojourners including missionaries. Although missionary re-entry has been studied in depth for over 20 years, little is known about what makes a missionary resilient to the challenges experienced in the stressful re-entry environment. Research suggests there are psychological, social, spiritual, and biological constructs connected with resilience. The aim of this paper is to answer the question “Why do some re-entering missionaries do well while others do not?” Fifteen adult Australian Christian cross-cultural missionary workers from four interdenominational Australian evangelical mission organisations completed semi-structured interviews and a survey. Results were analysed in two stages using modified consensual qualitative research methods. Links were established between resilience on re-entry and flexibility, expectancy, self-determination, denial using minimisation, mental health, social support, reintegration and personal spiritual connection with God. Implications for missionary care are discussed with suggestions for further research.