Resistant starch in the diet increases breath hydrogen and serum acetate in human subjects

Jane G. Muir, Zhong Xian Lu, Graeme P. Young, David Cameron-Smith, Greg R. Collier, Kerin O'Dea

Research output: Contribution to journalArticle

88 Citations (Scopus)

Abstract

The colonic fermentation of two diets differing in amounts of resistant starch (RS) was studied. High- and low-RS diets were fed to eight healthy subjects in three meals for 1 d. Breath hydrogen and two blood samples were collected over a 28-h period. The high-RS diet provided 59.1 ± 4.7 g (x̄ ± SE) RS and the low-RS diet provided 5.2 ± 0.4 g RS. Breath hydrogen and the average total serum acetate were significantly higher during the high-RS diet than during the low-RS diet: 34.1 ± 4.7 and 23.9 ± 3.9 ppm (P < 0.001) and 169.1 ± 12.8 and 118 ± 6.6 μmol/L (P < 0.01), respectively. Butyrate and propionate were also detected in serum samples. Although not statistically significant, there was a trend (P = 0.087) for butyrate to increase with the high-RS diet. Subjects reported greater gastrointestinal symptoms during the high-RS diet. These results suggest that RS may have effects comparable with those of some fermentable dietary fibers.

Original languageEnglish
Pages (from-to)792-799
Number of pages8
JournalAmerican Journal of Clinical Nutrition
Volume61
Issue number4
DOIs
Publication statusPublished - Apr 1995
Externally publishedYes

Keywords

  • breath hydrogen
  • Colonic fermentation
  • green banana flour
  • high- and low-amylose maize starch
  • resistant starch
  • serum acetate
  • serum butyrate
  • serum propionate
  • unprocessed wheat

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