Review of the Ophthalmic Manifestations of Gout and Uric Acid Crystal Deposition.

Jack Ao, Fiona Goldblatt, Robert Casson

Research output: Contribution to journalReview articlepeer-review

4 Citations (Scopus)


Gout is a clinical disorder that is characterized by the deposition of monosodium urate crystals (MSU) in joints and tendons, usually in the presence of prolonged hyperuricaemia. Following an asymptomatic phase of hyperuricaemia, gout usually presents as acute monoarthritis followed by periods of remission and exacerbation. Conjunctival hyperaemia and subconjunctival haemorrhage exacerbated by purine intake are two of the more common manifestations that may go unrecognized. Other ocular and adnexal structures can be affected by urate crystal deposition and associated inflammation, with potentially vision-threatening consequences; however, ocular manifestations of gout are rare and may have been over-reported in the older literature, but our understanding of the clinic-pathological features of ocular urate deposits remains limited.

Original languageEnglish
Pages (from-to)73-80
Number of pages8
JournalClinical and Experimental Ophthlamology
Issue number1
Publication statusPublished - 2017


  • eyes
  • gout
  • manifestations
  • ocular
  • ophthalmic


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