Risk Factor Management and Atrial Fibrillation Clinics: Saving the Best for Last?

Rajiv Mahajan, Rajeev K. Pathak, Anand Thiyagarajah, Dennis H. Lau, Francis E. Marchlinski, Sanjay Dixit, John D. Day, Jeroen M.L. Hendriks, Melinda Carrington, Jonathan M. Kalman, Prashanthan Sanders

Research output: Contribution to journalReview articlepeer-review

18 Citations (Scopus)


Atrial fibrillation (AF) is a leading cause of cardiovascular morbidity and mortality worldwide. Management of AF is a complex process involving: 1) the prevention of thromboembolic complications with anticoagulation; 2) rhythm control; and 3) the detection and treatment of underlying heart disease. However, cardiometabolic risk factors, such as obesity, hypertension, diabetes mellitus, and obstructive sleep apnoea, have been proposed as contributors to the expanding epidemic of atrial fibrillation (AF). Thus, a fourth pillar of AF care would include aggressive targeting of interdependent, modifiable cardiovascular risk factors as part of an integrated care model. Such risk factor management could retard and reverse the pathological processes underlying AF and reduce AF burden.

Original languageEnglish
Pages (from-to)990-997
Number of pages8
JournalHeart, Lung and Circulation
Issue number9
Publication statusPublished - Sept 2017
Externally publishedYes


  • Atrial fibrillation
  • Atrial remodelling
  • Cardiovascular risk factors


Dive into the research topics of 'Risk Factor Management and Atrial Fibrillation Clinics: Saving the Best for Last?'. Together they form a unique fingerprint.

Cite this