Ruxolitinib withdrawal complicating emergency aortic root replacement

Malgorzata (Maggie) Szpytma, Damian Gimpel, Gareth Crouch, Jayme S. Bennetts

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Ruxolitinib, a Janus kinase inhibitor, is associated with severe withdrawal phenomena. Adequate tapering is often underemphasized in surgical emergencies and can complicate the postoperative course. We present a case of acute ruxolitinib withdrawal in a gentleman undergoing emergency cardiac surgery.

Original languageEnglish
Article numberivac143
Number of pages3
JournalInteractive Cardiovascular and Thoracic Surgery
Issue number1
Publication statusPublished - Jul 2022


  • Aortic syndrome
  • Cardiac surgery
  • Ruxolitinib


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