Abstract
To the Editor:
We read with great interest the letter by Pauls et al. regarding the possible risk of andexanet alfa-related heparin resistance and recommendations made in the 2021 Society of Thoracic Surgeons (STS)-Society of Cardiovascular Anesthesiologists (SCA)-American Society of ExtraCorporeal Technology (AmSECT)-Society for the Advancement of Blood Management (SABM) Update to the Clinical Practice Guidelines on Patient Blood Management. In the recent guideline, a recommendation is proposed for the administration of a specific reversal antidote (ie, idarucizumab for dabigatran or andexanet alfa for either apixaban or rivaroxaban) to patients requiring emergent cardiac surgery with recent ingestion of a nonvitamin K oral anticoagulant or laboratory evidence of its effect. This guideline also makes recommendations to avoid bleeding after cardiopulmonary bypass. We agree that the timing of this intervention is important...
We read with great interest the letter by Pauls et al. regarding the possible risk of andexanet alfa-related heparin resistance and recommendations made in the 2021 Society of Thoracic Surgeons (STS)-Society of Cardiovascular Anesthesiologists (SCA)-American Society of ExtraCorporeal Technology (AmSECT)-Society for the Advancement of Blood Management (SABM) Update to the Clinical Practice Guidelines on Patient Blood Management. In the recent guideline, a recommendation is proposed for the administration of a specific reversal antidote (ie, idarucizumab for dabigatran or andexanet alfa for either apixaban or rivaroxaban) to patients requiring emergent cardiac surgery with recent ingestion of a nonvitamin K oral anticoagulant or laboratory evidence of its effect. This guideline also makes recommendations to avoid bleeding after cardiopulmonary bypass. We agree that the timing of this intervention is important...
Original language | English |
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Pages (from-to) | 1332-1334 |
Number of pages | 3 |
Journal | Journal of Cardiothoracic and Vascular Anesthesia |
Volume | 37 |
Issue number | 7 |
Early online date | 5 Mar 2023 |
DOIs | |
Publication status | Published - Jul 2023 |
Keywords
- cardiac disease
- thoracic surgery