Scheimpflug-Placido topographer and optical low-coherence reflectometry biometer: repeatability and agreement

Wuhe Chen, Colm McAlinden, Konrad Pesudovs, Qinmei Wang, Fan Lu, Y Feng, Jie Chen, Jinhai Huang

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    72 Citations (Scopus)


    Purpose: To assess the repeatability of common measurements with the Sirius Scheimpflug-Placido topographer and Lenstar LS900 optical low-coherence reflectometry (OLCR) biometer and the limits of agreement (LoA) between the devices. Setting: Eye Hospital of Wenzhou Medical College, Wenzhou, China. Design: Comparative evaluation of a diagnostic test or technology. Methods: One randomly healthy eye of subjects was scanned 3 times with both devices. The parameters assessed were central corneal thickness (CCT), anterior chamber depth (ACD) from the corneal epithelium and from the endothelium, mean keratometry (K), and white-to-white (WTW) corneal diameter. The repeatability of scans was calculated using the within-subject standard deviation after 1-way analysis of variance was performed. The agreement between devices was assessed using the Bland-Altman LoA method, which equals the mean difference between devices ± 1.96 × standard deviation of the differences. The mean of 3 scans of each device was used to assess the LoA. Results: Forty subjects were evaluated. The repeatability of the Scheimpflug-Placido topographer and OLCR biometer was 3.10 μm and 3.32 μm for CCT, 0.04 mm and 0.05 mm for WTW corneal diameter, and 0.17 D and 0.10 D for mean K, respectively. The repeatability for both devices was 0.02 mm for the ACD from the corneal epithelium and the ACD from the corneal endothelium. On Bland-Altman LoA analysis, all parameters were within clinically acceptable limits. Conclusion: Both devices had excellent repeatability for all parameters assessed. Good LoAs were found between the 2 devices, indicating they can be used interchangeably for the parameters assessed. Financial Disclosure: No author has a financial or proprietary interest in any material or method mentioned.

    Original languageEnglish
    Pages (from-to)1626-1632
    Number of pages7
    JournalJournal of Cataract and Refractive Surgery
    Issue number9
    Publication statusPublished - Sept 2012


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