Abstract
Several cytotoxic drugs were tested for their ability to produce permanent residual damage to the bone marrow. A short course of the drug was given to BALB/c female mice, and the numbers of various types of bone marrow cells were determined at least two months later. Evidence of residual damage was found after administration of busulfan and 1, 3-bis(chloroethyl)-1-nitrosourea, but not after administration of cyclophosphamide, 5-fluorouracil, 6-mercaptopurine, methotrexate, or vinblastine.
| Original language | English |
|---|---|
| Pages (from-to) | 1237-1239 |
| Number of pages | 3 |
| Journal | Journal of the National Cancer Institute |
| Volume | 57 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - Dec 1976 |
| Externally published | Yes |
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