The ABC-06 trial is an important, prospective, randomised phase 3 clinical trial that examined the role of second-line chemotherapy in advanced biliary tract cancers.1 Angela Lamarca and colleagues randomly assigned 162 patients to active symptom control (ASC) and FOLFOX chemotherapy (folinic acid, fluorouracil, and oxaliplatin) or ASC alone. Although the study met its endpoint, the improvement in overall survival was modest....
- FOLFOX chemotherapy
- biliary tract cancer
- intrahepatic cholangiocarcinomas