Second-, minute- and hour-metronomes of intestinal pacemakers

Robert A.R. Bywater, Nick J. Spencer, Rose Fida, Grahame S. Taylor

Research output: Contribution to journalArticlepeer-review

17 Citations (Scopus)


1. Movements of the gastrointestinal tract are required for the digestion of food and the expulsion of waste products. 2. The present paper will discuss the nature of electrical rhythms underlying some intestinal motility patterns. 3. The rhythms are generated by pacemakers with cycle rates appropriate to controlling individual contractions, motor patternings or switching between different motor programmes. 4. Electrical rhythms are discussed with periods of the order of seconds, minutes and hours. 5. Particular discussion is centred on rhythms recorded from the small and large intestine of the mouse.

Original languageEnglish
Pages (from-to)857-861
Number of pages5
JournalClinical and Experimental Pharmacology and Physiology
Issue number10
Publication statusPublished - Oct 1998
Externally publishedYes


  • Biological clocks
  • Colon
  • Enteric nervous system
  • Mice
  • Neurotransmission
  • Smooth muscle


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