Selective deposition of CaCO3 on chemical gradient surface generated by plasma polymerization and its effect on cell adhesion

Xujie Liu, Tarek A. Elkhooly, Ranran Zhang, Qingling Feng, Akash Bachhuka, Krasimir Vasilev, Qiang Cai, Shengli Mi

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

Calcic bioceramics have been widely used as substitutes or filling materials in bone grafts. Among them, CaCO3 is also favored due to its good biocompatibility and biodegradability. Herein, combined with chondroitin sulfate, CaCO3 can be selectively deposited on a chemical gradient surface generated by plasma polymerization. The chemical gradient in amino groups resulted in a gradient in deposited calcites number. The cell adhesion and spreading of SaoS-2 cells increased across the gradient surface with the increase of calcites number. These findings provide a controllable way to generate gradient CaCO3 coatings on scaffolds and/or implants used for bone regeneration.

Original languageEnglish
Pages (from-to)90-93
Number of pages4
JournalMaterials Letters
Volume186
DOIs
Publication statusPublished - 1 Jan 2017
Externally publishedYes

Bibliographical note

Funding Information:
The authors are grateful for the financial support from National Natural Science Foundation of China ( 31600763 and 51472139 ), and Project of Basic Research of Shenzhen ( JCYJ20160531195524566 ).

Publisher Copyright:
© 2016 Elsevier B.V.

Keywords

  • Adhesion
  • Bioceramics
  • Bone regeneration
  • Calcium carbonate
  • Plasma polymerization

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