Sequential injection analysis: an alternative approach to process analytical chemistry

Neil W. Barnett, Claire E. Lenehan, Simon W. Lewis

Research output: Contribution to journalArticlepeer-review

39 Citations (Scopus)


Flow injection analysis (FIA) is well established as a powerful sample handling procedure for laboratory and process analytical chemistry, but the latter application is often hampered by the complexity of the required manifolds particularly for multicomponent analyses. In certain circumstances multicomponent process analytical chemistry is only feasible by utilising several independent FIA systems. This review presents an overview of sequential injection analysis (SIA), which addresses these limitations, and applications of the methodology to the challenging area of process analytical chemistry will be discussed. Copyright (C) 1999 Elsevier Science B.V.

Original languageEnglish
Pages (from-to)346-353
Number of pages8
JournalTrAC - Trends in Analytical Chemistry
Issue number5
Publication statusPublished - May 1999
Externally publishedYes


  • On-line analysis
  • Process analytical chemistry
  • Sequential injection analysis


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