Serum Alkaline Phosphatase in Pregnancy: An Immunological Study

Donald J. Birkett; James Done; Francis C. Neale; Solomon Posen

doi:10.1136/bmj.1.5497.1210

Serum Alkaline Phosphatase in Pregnancy: An Immunological Study

Donald J. Birkett, James Done, Francis C. Neale, Solomon Posen

Research output: Contribution to journal › Letter › peer-review

25 Citations (Scopus)

Abstract

Alkaline phosphatase in maternal sera at term is partially inactivated by an anti-human placental alkaline phosphatase antibody. No such inactivation is seen in sera from nonpregnant subjects or newborn infants. This provides strong evidence that serum alkaline phosphatase elevation in pregnancy is due to circulating placental enzyme.

Original language	English
Pages (from-to)	1210-1212
Number of pages	3
Journal	British Medical Journal
Volume	1
Issue number	5497
DOIs	https://doi.org/10.1136/bmj.1.5497.1210
Publication status	Published - May 1966
Externally published	Yes

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@article{25e75b7af4d74eb9ac97c5de65ae2e15,

title = "Serum Alkaline Phosphatase in Pregnancy: An Immunological Study",

abstract = "Alkaline phosphatase in maternal sera at term is partially inactivated by an anti-human placental alkaline phosphatase antibody. No such inactivation is seen in sera from nonpregnant subjects or newborn infants. This provides strong evidence that serum alkaline phosphatase elevation in pregnancy is due to circulating placental enzyme.",

author = "Birkett, {Donald J.} and James Done and Neale, {Francis C.} and Solomon Posen",

year = "1966",

month = may,

doi = "10.1136/bmj.1.5497.1210",

language = "English",

volume = "1",

pages = "1210--1212",

journal = "British Medical Journal",

issn = "0007-1447",

publisher = "BMJ Publishing Group Ltd",

number = "5497",

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TY - JOUR

T1 - Serum Alkaline Phosphatase in Pregnancy

T2 - An Immunological Study

AU - Birkett, Donald J.

AU - Done, James

AU - Neale, Francis C.

AU - Posen, Solomon

PY - 1966/5

Y1 - 1966/5

N2 - Alkaline phosphatase in maternal sera at term is partially inactivated by an anti-human placental alkaline phosphatase antibody. No such inactivation is seen in sera from nonpregnant subjects or newborn infants. This provides strong evidence that serum alkaline phosphatase elevation in pregnancy is due to circulating placental enzyme.

AB - Alkaline phosphatase in maternal sera at term is partially inactivated by an anti-human placental alkaline phosphatase antibody. No such inactivation is seen in sera from nonpregnant subjects or newborn infants. This provides strong evidence that serum alkaline phosphatase elevation in pregnancy is due to circulating placental enzyme.

UR - http://www.scopus.com/inward/record.url?scp=0014014550&partnerID=8YFLogxK

U2 - 10.1136/bmj.1.5497.1210

DO - 10.1136/bmj.1.5497.1210

M3 - Letter

C2 - 5933831

AN - SCOPUS:0014014550

SN - 0007-1447

VL - 1

SP - 1210

EP - 1212

JO - British Medical Journal

JF - British Medical Journal

IS - 5497

ER -

Serum Alkaline Phosphatase in Pregnancy: An Immunological Study

Abstract

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